Publications:

Ouyang M., Lu S., Li X.-Y., Xu J., Seong J., Giepmans B.N., Shyy J.Y-J., Weiss SJ, Wang Y., (2008) Visualization of Polarized MT1-MMP Activity in Live Cells by FRET, Journal of Biological Chemistry, Accepted

Na S., Collin O., Chowdery F., Tay B., Ouyang M., Wang Y., Wang N., (2008) Rapid signal transduction in living cells is a unique feature of mechanotransduction. Proc Natl Acad Sci USA. In Press

Wang, Y., Shyy Y.-J., Chien, S. (2008) Fluorescence Proteins, Live Cell Imaging, and Mechanobiology: Seeing is Believing, Annual Review in Biomedical Engineering, In Press

Wang Y., Lu S. (2008) The Application of FRET Biosensors to Visualize Src Activation.

Proc. of SPIE. In Press

Wang Y., Shyy, J.-Y., and Chien, S., (2008) “Fluorescence Live-Cell Imaging: Principles and Applications in Mechanobiology”. Bioengineering in Cell and Tissue Research, In Press

Wang Y. and Chien, S., “Analysis of Integrin Signaling by Fluorescence Resonance Energy Transfer”. (2007) Methods in Enzymology, 426:177-201

Botvinick, EL and Wang Y., “Laser Tweezers in the Study of Mechanobiology in Live Cells”. (2007) Methods in Cell Biology, 82:497-523

Wang Y., Chang JM., Chen K.-D., Li S., Li J., Wu C., Chien S. (2007) Selective Adapter Recruitment and Differential Signaling Networks by VEGF vs. Shear Stress. Proc Natl Acad Sci USA. 104 (21): 8875-9

Larina IV., Wang Y., Chien S., Lane ME., and Dickinson ME. (2007) On the way to subcellular imaging of mechanotransduction in the developing vasculature. Proc. of SPIE. 6535 (653504):1-6

Hu YL., Haga JH., Miao H., Wang Y., Li YS., Chien S. (2006) Roles of microfilaments and microtubules in paxillin dynamics. Biochem Biophys Res Commun. 348(4):1463-71.

Wang Y., Jin G., Miao H., Li J., Usami S., Chien S. (2006) Integrins Regulate VE-cadherin and Catenins: Dependence of This Regulation on Src, but not on Ras. Proc Natl Acad Sci USA. 103(6):1774-79.

Wang Y., Botvinick E., Zhao Y., Berns M., Usami S., Tsien R.Y., Chien S. (2005) Visualization of Mechanical Activation of Src. Nature. 434:1040.

Miao H., Hu Y., Shiu Y.-T., Yuan S., Zhao Y., Kaunas R., Wang Y., Jin G., Usami S., and Chien S. (2005) Effects of Flow Patterns on the Localization and Expression of VE-Cadherin at Vascular Endothelial Cell Junctions: In-vivo and In-vitro Investigations. Journal of Vascular Research. 42:77.

Wang Y., Chang JM., Li Y.-C., Li Y.-S., Shyy J. Y.-J., and Chien S. (2004) Shear Stress and VEGF Activate IKK via Flk-1/Cbl/Akt Signaling Pathway. Am J Physiol Heart Circ Physiol. 286(2):H685-92.

Shiu Y.-T., Li S., Yuan S., Wang Y., Nguyen P., Chien S. (2003) Shear stress-induced c-fos activation is mediated by Rho in a calcium-dependent manner. Biochem Biophys Res Commun. 303(2):548-55

Wang Y., Miao H., Li S., Chen K.-D., Li Y.-S., Yuan S., Shyy J. Y.-J., and Chien S., (2002) Interplay between integrins and FLK-1 in shear stress- induced signaling. Am J Physiol Cell Physiol. 283: C1540-1548

Miao H., Yuan S., Wang Y., Tsygankov A., Chien S. (2002) Role of Cbl in Shear-Activation of PI 3-kinase and JNK in Endothelial Cells. Biochem Biophys Res Commun. 292(4):892-9

Li S., Butler P., Wang Y., Hu Y., Han D., Usami S., Guan J.-L., Chien S. (2002). The role of the dynamic of focal adhesion kinase in the mechanotaxis of endothelial cells. Proc Natl Acad Sci USA 99(6):3546-51

Wu W., Wang Y., Yan Z., Wen G. (1999). The Dynamic Coupling Model for the Whole Circulation in Human Body. Acta Scientiarum Naturalium, Universitatis Pekinensis 35(3): 328-339

Wu W., Wen G., Yan Z., Wang Y., Zhang, Z. (1999). The Dynamic Coupling of Right Ventricle and Pulmonary Arteries. Acta Scientiarum Naturalium, Universitatis Pekinensis 35(3): 317-327

Wang Y., Wu W., Wen G. (1998). The Influence of Cardiovascular Dynamic Coupling on the Blood Pulse Wave Propagation in Human Body. Applied Mathematics and Mechanics 19(7):601-614